
Chlorogenic Acid
CAS No. 327-97-9
Chlorogenic Acid ( 3-O-Caffeoylquinic acid | Heriguard | NSC 407296 )
产品货号. M14069 CAS No. 327-97-9
绿原酸(NSC-407296;3-O-咖啡酰奎尼酸)是人类饮食中最丰富的多酚之一,据报道可抑制 Y 细胞生长,也是金银花提取物的主要抗炎成分。
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
500MG | ¥405 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Chlorogenic Acid
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述绿原酸(NSC-407296;3-O-咖啡酰奎尼酸)是人类饮食中最丰富的多酚之一,据报道可抑制 Y 细胞生长,也是金银花提取物的主要抗炎成分。
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产品描述Chlorogenic acid(NSC-407296; 3-O-Caffeoylquinic acid) is one of the most abundant polyphenols in the human diet, has been reported to inhibit Y cell growth and a major anti-inflammatory constituent of lonicerae flos extract.
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体外实验——
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体内实验Animal Model:Experimental reflux esophagitis (RE) in ratsDosage:10, 30, 100 mg/kg Administration:p.o.Result:Reduced esophageal lipid peroxidation (marker: MDA) and increased the reduced glutathione/oxidized glutathione ratio. Inhibited the increases in the serum level of TNF-α, and expressions of iNOS and COX-2 protein.Animal Model:LPS/GalN-challenged mice Dosage:10 mg/kg Administration:i.v.Result:Increased survival rates of LPS/GalN-intoxicated mice.Inhibited LPS/GalN-induced phosphorylation of NF-κB p65 or c-Jun, without affecting p-IRF3 levels in the liver lobules.
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同义词3-O-Caffeoylquinic acid | Heriguard | NSC 407296
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通路Others
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靶点Other Targets
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受体Others
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研究领域Inflammation/Immunology
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适应症——
化学信息
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CAS Number327-97-9
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分子量354.32
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分子式C16H18O9
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纯度>98% (HPLC)
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溶解度Ethanol: 71 mg/mL (200.38 mM); Water: 18 mg/mL (50.8 mM); DMSO: 71 mg/mL (200.38 mM)
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SMILESO=C([C@@]1(O)C[C@@H](OC(/C=C\C2=CC=C(O)C(O)=C2)=O)[C@H](O)[C@H](O)C1)O
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化学全称(1S,3R,4R,5R)-3-{[(2Z)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-1,4,5-trihydroxycyclohexanecarboxylic acid
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
1. Illing EA, et al. Otolaryngol Head Neck Surg. 2015 Aug;153(2):291-7.