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Chlorogenic Acid

CAS No. 327-97-9

Chlorogenic Acid ( 3-O-Caffeoylquinic acid | Heriguard | NSC 407296 )

产品货号. M14069 CAS No. 327-97-9

绿原酸(NSC-407296;3-O-咖啡酰奎尼酸)是人类饮食中最丰富的多酚之一,据报道可抑制 Y 细胞生长,也是金银花提取物的主要抗炎成分。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
500MG ¥405 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Chlorogenic Acid
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    绿原酸(NSC-407296;3-O-咖啡酰奎尼酸)是人类饮食中最丰富的多酚之一,据报道可抑制 Y 细胞生长,也是金银花提取物的主要抗炎成分。
  • 产品描述
    Chlorogenic acid(NSC-407296; 3-O-Caffeoylquinic acid) is one of the most abundant polyphenols in the human diet, has been reported to inhibit Y cell growth and a major anti-inflammatory constituent of lonicerae flos extract.
  • 体外实验
    ——
  • 体内实验
    Animal Model:Experimental reflux esophagitis (RE) in ratsDosage:10, 30, 100 mg/kg Administration:p.o.Result:Reduced esophageal lipid peroxidation (marker: MDA) and increased the reduced glutathione/oxidized glutathione ratio. Inhibited the increases in the serum level of TNF-α, and expressions of iNOS and COX-2 protein.Animal Model:LPS/GalN-challenged mice Dosage:10 mg/kg Administration:i.v.Result:Increased survival rates of LPS/GalN-intoxicated mice.Inhibited LPS/GalN-induced phosphorylation of NF-κB p65 or c-Jun, without affecting p-IRF3 levels in the liver lobules.
  • 同义词
    3-O-Caffeoylquinic acid | Heriguard | NSC 407296
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    Others
  • 研究领域
    Inflammation/Immunology
  • 适应症
    ——

化学信息

  • CAS Number
    327-97-9
  • 分子量
    354.32
  • 分子式
    C16H18O9
  • 纯度
    >98% (HPLC)
  • 溶解度
    Ethanol: 71 mg/mL (200.38 mM); Water: 18 mg/mL (50.8 mM); DMSO: 71 mg/mL (200.38 mM)
  • SMILES
    O=C([C@@]1(O)C[C@@H](OC(/C=C\C2=CC=C(O)C(O)=C2)=O)[C@H](O)[C@H](O)C1)O
  • 化学全称
    (1S,3R,4R,5R)-3-{[(2Z)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}-1,4,5-trihydroxycyclohexanecarboxylic acid

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1. Illing EA, et al. Otolaryngol Head Neck Surg. 2015 Aug;153(2):291-7.
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